July 28, 2016

Uveitis is a condition in which there is inflammation involving the uvea of the eye. The uvea is made up of the iris, ciliary body and choroid. It contains many blood vessels and is important for nourishing the eye. Therefore, when inflammation involves the uvea, vision can be affected. When the front of the eye or the iris is involved, this is called anterior uveitis or iritis and can result in blurry vision, redness, sunlight sensitivity and eye discomfort. When the ciliary body is involved, this is called intermediate uveitis and may cause blurry vision or floaters. When the retina or choroid is primarily involved, this is called posterior uveitis and can result in blurry vision or, in severe cases, blindness. When all parts of the eye are involved, this is referred to as panuveitis. It is important to know that uveitis may not cause any symptoms and may only be diagnosed on exam with your eye doctor. Uveitis can affect one or both eyes and usually affects adults 20-60 years old but may also affect children.

Current Clinical Trials for Uveitis:

Santen, Inc. 32-007:

A Phase 3, multinational, multicenter, randomized, double-masked, study assessing the safety and efficacy of intravitreal injections of DE-109 (three doses) for the treatment of active, non-infectious uveitis of the posterior segment of the eye. *This is closed for enrollment.